BDBM13080 CGS 27023A Analog 3::N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]acetamide::US20230357139, Compound A::US20240050571, Compound NNGH
SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO
InChI Key InChIKey=JIRXORZYIXSWOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 13080
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MMP2 using BML-P125-9090 as substrate after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human MMP2 using thiopeptide as substrate preincubated for 30 mins followed by substrate addition and measured every mins f...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of MMP-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-PLGLDpaAR fluorescent substrate incubated for 2 hrs by microplate reader methodMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to testing measured for 15...More data for this Ligand-Target Pair